It is unclear whether Moore will return for next Sunday’s MCG match against West Coast.
“We’ll let the dust settle on his first game back,” said coach Nathan Buckley.
The Eagles could regain star forwards Josh Kennedy and Jack Darling from injury for the big clash, with the two teams in the top four.
Hoskin-Elliott has a badly bruised shin and Appleby is nursing a hamstring injury after Sunday’s bruising win over Essendon at the MCG.
The Bombers also lost Patrick Ambrose to a hamstring injury, while Jake Stringer and Travis Myer played out the game with calf muscle problems.
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Hawthorn are set to lose in-form ruckman Ben McEvoy for several weeks with a suspected fracture cheekbone.
McEvoy went to hospital after suffering the injury during Saturday night’s win over the Western Bulldogs.
Richmond defender Nathan Broad also hurt his cheekbone on Friday night in the win over Adelaide, while Jack Graham has a dislocated shoulder.
Crows defender Daniel Talia was able to play out the game, but clearly was struggling with a foot injury.
Sydney lost Jarrad McVeigh (collarbone) and Dan Hannebery (calf) in the loss to Geelong, but Kieren Jack (knee) might be available for next Sunday’s match against North Melbourne at Etihad Stadium.